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Genetic susceptibility mechanisms. Most susceptibility loci map to non-coding locations with the genome, are generally located in active promoters or enhancers, and modify the binding web pages of numerous transcription factors.

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Preliminary chromosome banding Investigation exposed that deletions or trisomies were rather prevalent but only observed in fewer than half in the people.forty six With the advent of fluorescent in situ

mutations and sophisticated kar yotype. It follows a linear evolution within the CLL clone through the recurrent acquisition of CDKN2A

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